POTENTIAL PRODROMAL DIGITAL POSTURAL SWAY MARKERS FOR FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME (FXTAS) DETECTED VIA DUAL-TASKING AND SENSORY MANIPULATION

Potential Prodromal Digital Postural Sway Markers for Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) Detected via Dual-Tasking and Sensory Manipulation

FXTAS is a neurodegenerative disorder occurring in some Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene premutation carriers (PMCs) and is characterized by cerebellar ataxia, tremor, and cognitive deficits that negatively impact balance and gait and increase fall risk.Dual-tasking (DT) cognitive-motor paradigms and challenging balance condition

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Nuclear RNA surveillance complexes silence HIV-1 transcription.

Expression from the HIV-1 LTR can be repressed in a small population of cells, VENAFORCE GEL which contributes to the latent reservoir.The factors mediating this repression have not been clearly elucidated.We have identified a network of nuclear RNA surveillance factors that act as effectors of HIV-1 silencing.RRP6, MTR4, ZCCHC8 and ZFC3H1 physical

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